New drug developments are exciting; they cure disease and often alleviate difficult problems. Such was the case when Viagra and Cialis were created to cure erectile dysfunction. For a little longer than forever, men who have suffered this personal and embarrassing disorder have had to either avoid sexual encounters or employ less then pleasant alternatives.

This innovation allowed men to engage, and enjoy sexual relations. However, with every advance, potential side effects can occur. Men with cardiovascular disease or who take certain medicines are at risk for serious systemic complications, with these medications.

This class of drugs is called selective phodiesterase type 5 inhibitors because they treat the erectile dysfunction by interfering with the action of this compound on the vasculature in the penis. The problem that arose was this same reaction takes place in the retina. Mild but transient blurry vision, altered light perception, and a blue hue in one’s vision are common complaints in men taking this class of drug. Long term use has resulted, in some cases, in non-arteritic anterior ischemic neuropathy, central serous chorioretinopathy, and other vascular related changes. Scientists have concluded that these side affects result from off target inhibition of PDE6 which is very similar to PDE5 and is involved in regulation of photo transduction.

The good news is that according to a study published in the April issue of Archives of Ophthalmology, conducted by Eli Lily Research Labs, these changes are temporary and transient. They stated that there is no long term damage to the retina or visual system when using this class of medication. It should be noted that the study only followed these men for a period of 6 months. As with all medications, follow the doctor’s instructions and guidelines, stop taking it if there are any problems and seek medical help if any symptom does not resolve in a reasonable period of time.